ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will raise the level or influence of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Acute ergot toxicity characterized by vasospasm and tissue ischemia is connected with coadministration of ritonavir It's important to note that Bizarro K2 is prohibited in